The injection of the cells of marrow in the heart the 'muscular wall of S.A. reconstituted the flow of blood in the hearts with the blocked arteries for which the conventional treatments had proven the ineffective and Dutch doctors paid.

I think that they is very good news for the patients who are at the end of the line and do not make leave any option, Dr. says Douwe E. Atsma, a cardiologist of interventional at the medical centre of university of Leyde and an author of the study, which appears in the edition of May 20 of the newspaper of American Medical Association.

The 50 people in the study, 43 of them of the men, tested the angina, or the serious pain of trunk, because of fillings in their arteries of heart. All had undergone several procedures of artery-opening, such as the angioplastie or surgery of deviation, to reconstitute the flow of blood, but such measurements would not help them any more, Atsma indicated.

Half of the participants received injections of the cells taken of their own marrow, and the others received the inactive injections of cells. After three months, the answers were varied, with some participants bringing back the complete relief and others with the partial advantages.

Most important Chose is that the quantity of ischaemia [filling of artery] was divided into two in those indicated the cells of /courgette marrow, Atsma said. Quantit� of fabric with ischaemia was reduced, function of heart improved appreciably of a small manner and their categories of quality of life were higher.

Two earlier and smaller tests of therapy of cells of marrow for the cardiac disease had produced contradictory results, Atsma indicated. We are up to now the greatest test and the first to show a reduction in, of ischaemia it said.

The results were so good, Atsma stated, that the participants who had the factitious injections since were given the therapy of cells of marrow, and consider-now us that an option for patients in same, of condition it said.

The study excluded from the people with the cardiac arrest, which occurs when the muscle of heart became too weak to pump blood correctly. But Atsma indicated that a test of therapy of cells of marrow for the people who blocked arteries as the cardiac arrest is envisaged.

The injections of cells of marrow help to reconstitute the flow of blood by supporting the creation of new blood-vessels, Atsma indicated, but him 's nonclear how this occurs. It could be that the cells which are injected become part of vascularization, blood-vessels it said. Still better, the cells injected can secrete the proteins which stimulate the angiogen�se, formation of the blood-vessels. Or it could be a combination of these two things.

That which it reason with the profit of the therapy of cells of marrow, of us are rather enthusiastic, considering that these patients did not have any alternative, Atsma said. They had all the surgery and angioplastie which they could have.

Dr. Amit Patel, director of regenerating medicine cardiovascular at the university of Utah, described to find like certainly a step ahead in the treatment of the chronic angina. But had some comments of warning to him.

It was a small study, with Juste 50 participants says it adding that to make him a more reproducible therapy, you should make at least two or three hundred patients.

Moreover, the period of follow-up was relatively short, in three months, it noted. Something produced positive, but should follow these patients to you further to see how long it would last, Patel said. The future studies to determine if there would be a total improvement of function of heart would be also welcome, it said.

Dory Taylor, director of the university of the center of Minnesota for cardiovascular repair, also had qualified the praise for the results.

Bon news is that he is more mechanist because he gives some perspicacities in, of perfusion it said. It reinforces the obviousness which the cells of marrow are sure and effective. It also reinforces current wisdom that it is not a race of house. The results are positive, but it is not the panacea which we hoped for that it would be.

To promote the analogy of baseball, Taylor said that for people who feel better, I would consider it a double.

More studies are necessary to get information about the value of the therapy of cells through the complete spectrum of, of the cardiovascular disease it said. We must include/understand what we must do differently. I hope that these data cause this conversation.