A substance secreted by the eczema-damaged skin could start asthma in the children, the researchers of the United States propose.

The theory comes from a study of the mice with eczema-like the condition, which suggested that the treatment early of eczema and the inhibition of the substance of release could help to prevent asthma.

Of the 50 percent approximately to 70 percent of children with serious eczema, known under the name of dermatite atopic, develop the asthma, compared with approximately 9 percent of children in the global population. In the United States, approximately 17 percent of children have eczema, although not all the cases are serious.

The progression of eczema to asthma is called walk atopic.

During years, the clinical community fought to explain, atopic of walk Raphael Kopan, a professor of biology d�veloppementale and the dermatology at the Medical school of university of Washington with St Louis and an author of the study, indicated in a press release of the school.

Thus, when we noted that the skin of the mice with eczema-like the condition produced a substance previously implied in asthma, we decided to study more far, Kopan said. We noted that the mice also suffered from asthma-like answers to the inhaled allergens, implying the substance, called the TSLP, like bond between eczema and asthma.

The researchers noted that TSLP (lymphopoietin stromal thylmic) is secreted by the skin damaged to alert the body that the skin the 'barrier protective of failed S.A. TSLP activates an immunoreaction which fights invaders.

We are excited, because we the 'VE narrowed to the bottom the problem of walk atopic to one, of molecule Kopan said. Us the 'shown VE that the skin can act as a body of indication and lead the allergic ignition in the lung by releasing TSLP. Now, it will be important to address how to prevent the defective skin from producing TSLP.

If that can be made, it said, bond between eczema and asthma could be broken.

The study appears May 19 in the biology of PLoS of newspaper.